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Responsibilities:

1. Develop, validate, optimize and execute cell-based assays to support SAR in lead identification and optimization.

2. Design and carry out explorative, mechanistic research on oncogenic target validations, biomarker discovery, drug resistance and beyond

3. Analyze experimental data to evaluate new molecules’ potency in target engagement in cellular assays.

4. Maintain accurate records of experiments, analyze and interpret the results, present summaries, and generate reports of the studies.

5. Work in close collaboration with discovery team and communicate results in a timely manner.

6. Supervise research associates in designing, executing experimental plans.

Qualifications:

1. PhD in molecular biology, cell biology, cancer biology, immuno-oncology or other biological disciplines.

2. PhD (Preferred) with 5-10 experience in drug development or immunoncology research experience.

3. Experience with molecular/cell biology techniques such as immunoblots, in-cell western, ELISA and bio-luminescence as well as other detection methods.

4. Experience in cellular assay development, optimization, validations.

5. A major plus for expertise in flow cytometry and high content imaging techniques.

6. Ability to manage multiple projects and proficiency as a scientific leader that designs, execute or lead associate to execute, and manages research plans,

7. Highly independent and organized with proficient verbal and written communication skills